Nikon D300 vs Canon EOS R6 Mark II

This is a full comparison between the cameras Nikon D300 and Canon EOS R6 Mark II. We compare them by looking at the categories you see below.

Manufacturing

Nikon D300 is manufacturered by Nikon but Canon EOS R6 Mark II is from Canon. Both Nikon and Canon are well known brands though.

Type of camera

Nikon D300 is a DSLR camera while Canon EOS R6 Mark II is a Mirrorless camera. More information about their differences will come soon.

Sensors / crop factor

These cameras have different sensors. Nikon D300 has a "DX"-sensor while Canon EOS R6 Mark II has a "FF"-sensor, and their difference in sensors will also affect the crop factor and experience focal length. See the table below.

** Experienced focal length when using a lens such as a common "50mm f/1.8"

Learn more about crop factor and focal length multiplier here:
Camera selection can affect the focal length (Nikon)
Camera selection can affect the focal length (Canon)

Resolution

Nikon D300 has a 12,3 MP (Megapixels) resolution while Canon EOS R6 Mark II has 24 MP. If we break down this in more detail this is the data behind the numbers:

Canon EOS R6 Mark II has a 97 % larger resolution than Nikon D300. This could give you more details in the picture but also a possibility to crop more in the pictures, afterward while editing the pictures, if needed that is.

ISO range

Canon EOS R6 Mark II has a larger ISO-range than Nikon D300. Canon EOS R6 Mark II has an ISO range that stretches from 100 to 102400 while Nikon D300 has 200 to 6400.

Autofocus and lens compatibility

Both of these cameras have a built-in autofocus motor. Some lenses, that support autofocus, do not have an autofocus motor of their own but this won't cause any problems with these two cameras.

Worth mentioning is that Canon EOS R6 Mark II belongs to the Canon EOS R-system and needs an adapter to work with Canons EF, EF-S, MP-E, and TS-E lenses. You can read more about this adapter here:
Canon Lens Mount Adapter EF-EOS R

Here is a complete overview of which lenses work with each camera:
Lens compatibility chart for Nikon D300
Lens compatibility chart for Canon EOS R6 Mark II

Pictures per second

Depending on what you are shooting the FPS, or frames/pictures per second, can definitely be of interest. Nikon D300 can shoot up to 6 pictures per seconds and Canon EOS R6 Mark II can shoot up to 40 pictures per seconds.

Ability to record movies

It is becoming more and more popular to record movies with digital cameras.

It is only one of these two cameras that support recording movies and movie clips and that is Canon EOS R6 Mark II. Sadly, the Nikon D300 does not support this.

Weight

The weight of the camera can be an extremely important factor, especially if the camera is about to be used, or carried around, for several hours at a time.

Nikon D300 weighs 925 gr (equal to 2,04 lb) which is 38% heavier than Canon EOS R6 Mark II and its 670 gr (or 1,48 lb).